Table 5. Studies included in comparison of radiotherapy vs chemoradiotherapy.
Trial | Group | Median age and gender | Chemotherapy/radiotherapy used and dose |
---|---|---|---|
Moertel et al (1969) | Radiotherapy (n=32) | NA | 3500–4000 rad by cobalt 60 teletherapy unit |
Chemoradiotherapy (n=32) | NA | 3500–4000 rad by cobalt 60 teletherapy unit, 5FU 45 mg kg−1 on first 3 days of radiotherapy | |
Cohen et al (2005) | Radiotherapy (n=49) | 62 years; 55 men, 45 women | Radiotherapy 59.4 Gy |
Chemoradiotherapy (n=55) | 64 years; 67 men, 33 women | Radiotherapy 59.4 Gy, 5FU 1000 mg m−2 day−1 on days 2–5 and 28–31 of radiotherapy MMC 10 mg m−2 on day 2 |
MMC=mitomycin; 5FU=5-fluorouracil.