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. 2007 Mar 27;96(8):1265–1271. doi: 10.1038/sj.bjc.6603706

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Copyright © 2007 Cancer Research UK

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Detection of de novo germline CEB1 mutations in two family trios (A and B) following PCR and gel electrophoresis. Mutant alleles are indicated by white arrows. Family A has a paternal mutation corresponding to a seven repeat expansion. Family B has a paternal mutation corresponding to a one repeat deletion. To ensure accurate band comparison between adjacent lanes samples were loaded in the order father (F), child (C), mother (M).