Table 4. Children conceived by female HLSs treated with high gonadotoxic chemotherapy, for those who had attempted post-treatment parenthood (N=11).
Patient no. | Year of diagnosis | Age at diagnosis (years) | Chemotherapy | Radiotherapy (RT) | Achieved PtP | Age at birth of first child post-treatment (years) | No of children post-treatment |
---|---|---|---|---|---|---|---|
1 | 1976 | 9 | Six MVPP | SupRada+Paraaortic field | Yes | 24 | Three |
2 | 1979 | 18 | Six MVPP | SupRad | Yes | 29 | Two |
3 | 1988 | 17 | Six ChlVPP 2 ABOD | SupRad | Yes | 27 | Two |
4 | 1976 | 16 | Six MVPP | SupRad+Para-aortic field | Yes | 33b | Two |
5 | 1981 | 23 | Eight ChlVPP | No RT | Yes | 32 | Two (twins) |
6 | 1988 | 19 | Eight ChlVPP | SupRad | Yes | 28 | One |
7 | 1988 | 36 | Eight ChlVPP | No RT | No | ||
8 | 1990 | 35 | HDTc | SupRad | No | ||
9 | 1978 | 31 | Six MVPP | SupRad | No | ||
10 | 1971 | 32 | Eight MVPP8 CCNU po | Th10-12 3200 rtg/10 days | No | ||
11 | 1978 | 30 | Six MVPP | SupRad+Paraaortic field | No |
SupRad: supradiaphragmatic radiotherapy.
First child after RT only at 18 years, relaps at 19 years, second child at age 33 years.
HDT: high-dose chemotherapy with autologous stem cell support.