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. 2007 Apr 3;96(9):1442–1449. doi: 10.1038/sj.bjc.6603711

Table 4. Children conceived by female HLSs treated with high gonadotoxic chemotherapy, for those who had attempted post-treatment parenthood (N=11).

Patient no. Year of diagnosis Age at diagnosis (years) Chemotherapy Radiotherapy (RT) Achieved PtP Age at birth of first child post-treatment (years) No of children post-treatment
1 1976 9 Six MVPP SupRada+Paraaortic field Yes 24 Three
2 1979 18 Six MVPP SupRad Yes 29 Two
3 1988 17 Six ChlVPP 2 ABOD SupRad Yes 27 Two
4 1976 16 Six MVPP SupRad+Para-aortic field Yes 33b Two
5 1981 23 Eight ChlVPP No RT Yes 32 Two (twins)
6 1988 19 Eight ChlVPP SupRad Yes 28 One
7 1988 36 Eight ChlVPP No RT No    
8 1990 35 HDTc SupRad No    
9 1978 31 Six MVPP SupRad No    
10 1971 32 Eight MVPP8 CCNU po Th10-12 3200 rtg/10 days No    
11 1978 30 Six MVPP SupRad+Paraaortic field No    
a

SupRad: supradiaphragmatic radiotherapy.

b

First child after RT only at 18 years, relaps at 19 years, second child at age 33 years.

c

HDT: high-dose chemotherapy with autologous stem cell support.