Table 5. Multivariate analysis of clinicopathological and genetic parameters for OS (Cox regression hazard analysis).

	OS
Prognostic factor	P-values	Hazard ratio	95% CI
Step 1
pT category
T3/4	0.27	2	0.6–6.3
pN category
N2/3	0.001	2.3	1.4–3.8
Differentiation
G3/4	0.18	1.4	0.9–2.4
Treatment arm
Arm B (5-FU/LEV)	0.02	1.8	1.1–3.8
BSI
Low	0.004	2.1	1.3–3.4
Step 3
pN category
N2/3	<0.0001	2.5	1.5–4.2
BSI
Low	0.003	2.1	1.3–3.5
Treatment arm
Arm B (5-FU/LEV)	0.01	1.9	1.1–3.1

CI=confidence interval; 5-FU=5-fluorouracil; LEV=levamisole; OS=overall survival. Bold values signify P<0.05.