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. 2007 Apr 17;96(9):1425–1432. doi: 10.1038/sj.bjc.6603745

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Copyright © 2007 Cancer Research UK

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(A and B) In situ TUNEL for apoptotic cells (A) and MIB-1 staining for proliferating cells (B) in an OSCC with Pidd overexpression compared to normal oral epithelium (Pidd expression=4.09 relative units, AI=1.31%, PI=42%). (C and D) In situ TUNEL for apoptotic cells (C) and MIB-1 staining for proliferating cells (D) in an OSCC with Pidd underexpression compared to normal oral epithelium (Pidd expression=0.36 relative units, AI=0.03%, PI=19%). Apoptotic cells (A and C) and MIB-1 expressing cells (B and D) are stained brownish-red and the sections are counterstained with haematoxylin. Bar indicates 100 μm.