Table 2. Performance characteristics of the tumour M2-PK stool test at a cutoff value of 4 U ml−1 among patients with colorectal cancer.
Sensitivity
|
|||
---|---|---|---|
Patient group | Proportion of CRC cases tested positive | (%) | 95% confidence interval |
CRC | 44/65 | 68 | 55–79 |
Colon | 22/26 | 85 | 65–96 |
Rectum | 22/39 | 56 | 41–74 |
Proximala | 14/16 | 88 | 62–99 |
Distala | 30/49 | 61 | 46–75 |
T1b | 4/6 | 67 | 22–96 |
T2b | 7/16 | 44 | 20–70 |
T3b | 24/34 | 71 | 53–85 |
T4b | 4/4 | 100 | 40–100 |
Dukes' A | 8/12 | 67 | 35–90 |
Dukes' B | 11/18 | 61 | 36–83 |
Dukes' C | 8/12 | 67 | 35–90 |
Dukes' D | 6/6 | 100 | 54–100 |
Neoadjuvant therapy | |||
No | 33/48 | 69 | 54–81 |
Yes | 11/16 | 69 | 41–89 |
Abbreviations: CRC=colorectal cancer.
Proximal / distal to the splenic flexure.
T stage according to the TNM classification.