. 2007 Apr 3;96(9):1329–1334. doi: 10.1038/sj.bjc.6603712

Table 3. Distribution of subjects in the population sample (ESTHER study participants), and proportion of positive test results for faecal tumor M2-PK at a cutoff value of 4 U ml⁻¹ according to age, sex, body mass index, cigarette smoking status and family history of colorectal cancer.

	Proportion of ESTHER participants tested positive		P-value (χ² test)	Specificity (95% CI)
	196/917	21.4%		78.6% (75.8–81.2%)
Age group (years)
50–54	30/165	18.2%
55–59	34/150	22.7%
60–64	56/263	21.3%
65–69	42/194	21.6%
70–75	34/142	23.9%	0.789
Sex
Females	104/525	19.8%
Males	92/392	23.5%	0.181

Body mass index (kg m⁻²)
⩽25	45/243	18.5%
>25–30	78/398	19.6%
>30	67/262	25.6%	0.097

Cigarette smoking status
Never smoker	98/484	20.2%
Former smoker	45/258	17.4%
Current smoker	48/154	31.2%	0.003

Family history of CRC
First degree relative with CRC	13/68	19.1%
No first degree relative with CRC	183/849	21.6%	0.637

Table 3. Distribution of subjects in the population sample (ESTHER study participants), and proportion of positive test results for faecal tumor M2-PK at a cutoff value of 4 U ml−1 according to age, sex, body mass index, cigarette smoking status and family history of colorectal cancer.