Table 5. Risk of epithelial ovarian cancer among exclusive users of one hormone type (estrogen only and estrogen plus progestin).
Estrogen onlya
|
Estrogen plus progestina
|
|||
---|---|---|---|---|
<5 years use | ⩾5 years use | <5 years use | ⩾5 years use | |
All epithelial ovarian tumours | ||||
No. of cases | 39 | 43 | 22 | 10 |
Age-adjusted (95% CI) | 0.94 (0.66, 1.34) | 1.81 (1.28, 2.56) | 1.03 (0.64, 1.67) | 0.92 (0.47, 1.79) |
Multivariateb RR (95% CI) | 0.98 (0.68, 1.40) | 2.04 (1.41, 2.97) | 1.03 (0.64, 1.66) | 0.93 (0.47, 1.83) |
Abbreviations: RR, relative risk; CI, confidence interval; PMH, postmenopausal hormone.
Models include never PMH users and users of one hormone type only (exclusive users of unopposed estrogen and exclusive users of estrogen plus progestin).
Adjusted for age, parity, duration of oral contraceptive use, tubal ligation, age at natural menopause and age at menarche.