Table 3. Crude and adjusted mean micronucleus frequencies, stratified by BRCA1 mutation carriers and non-carriers.
|
Crude mean (±s.e.m.)
|
Adjusted meanb (±s.e.m.)
|
||||||
|---|---|---|---|---|---|---|---|
| Dose (Gy) | Time after irradiation (h) | BRCA1+/− | BRCA1WT | P a | BRCA1+/− | BRCA1WT | P a |
| 0 | 0 | 25.06 (3.39) | 18.00 (2.89) | 0.120 | 20.89 (3.26) | 19.96 (1.81) | 0.794 |
| 2 | 0 | 132.77 (12.39) | 128.84 (12.03) | 0.821 | 124.70 (4.69) | 139.79 (7.37) | 0.114 |
a
The Student's t-test used to test for differences in the crude and adjusted means of the tail moments between BRCA1 mutation carriers and non-carriers.
b
Multivariate linear regression included terms for age (years), BMI (kg m−2), current smoker (yes/no), alcohol intake (total drinks of per day), physical activity (total hours per week), and total daily caloric intake (kcal).