Table 2. Risk of breast cancer estimated as hazard ratios (HR) with 95% confidence intervals (CIs) for total fat, MUFA, PUFA and SFA for the entire cohort as well as for breast cancers occurring before or after 50 years of age.

	Quintiles
	Q1	Q2	Q3	Q4	Q5	Trend over categories (P)	Intake of continuous form per 10 g/day	P
Entire cohorta
Total fat
Median, g/day	30.8	42.9	52.4	63.1	80.7
(% energy)	(26)	(29)	(31)	(32)	(34)
Cases	208	198	193	206	169
HR (95% CI)b	1.00	0.99 (0.80–1.22)	1.01 (0.80–1.28)	1.13 (0.86–1.47)	1.02 (0.72–1.45)	0.70	1.04 (0.97–1.11)	0.32
MUFA
Median, g/day	10.4	14.4	17.5	21.0	26.5
(% energy)	(9)	(10)	(10)	(11)	(11)
Cases	206	202	205	189	172
HR (95% CI)b	1.00	0.98 (0.79–1.23)	1.01 (0.76–1.33)	0.95 (0.67–1.35)	0.88 (0.53–1.46)	0.65	0.82 (0.49–1.35)	0.43
PUFA
Median, g/day	4.3	6.0	7.3	8.7	11.2
(% energy)	(3.6)	(4.0)	(4.2)	(4.4)	(4.8)
Cases	209	201	191	205	168
HR (95% CI)b	1.00	0.93 (0.76–1.14)	0.89 (0.71–1.12)	0.92 (0.71–1.19)	0.72 (0.52–1.00)	0.08	0.83 (0.54–1.27)	0.40
SFA
Median, g/day	12.9	18.6	23.3	28.7	37.9
(% energy)	(11)	(12)	(14)	(15)	(16)
Cases	207	198	198	188	183
HR (95% CI)b	1.00	0.98 (0.78–1.23)	1.04 (0.79–1.36)	1.02 (0.73–1.44)	1.12 (0.69–1.81)	0.65	1.12 (0.84–1.49)	0.43
Breast cancer before the age 50 yearsc
Total fat
Median, g/day	30.8	42.9	52.4	63.1	80.7
(% energy)	(26)	(29)	(31)	(32)	(34)
Cases	78	83	82	99	90
HR (95% CI)b	1.00	1.10 (0.79–1.52)	1.12 (0.78–1.62)	1.44 (0.95–2.16)	1.46 (0.87–2.47)	0.10	1.06 (0.96–1.18)	0.22
MUFA
Median, g/day	10.4	14.4	17.5	21.0	26.5
(% energy)	(9)	(10)	(10)	(11)	(11)
Cases	76	84	93	84	95
HR (95% CI)b	1.00	1.16 (0.81–1.66)	1.35 (0.88–2.06)	1.30 (0.76–2.21)	1.69 (0.81–3.51)	0.20	1.31 (0.63–2.73)	0.47
PUFA
Median, g/day	4.3	6.0	7.3	8.7	11.2
(% energy)	(3.6)	(4.0)	(4.2)	(4.4)	(4.8)
Cases	78	80	94	97	83
HR (95% CI)b	1.00	0.99 (0.71–1.38)	1.16 (0.82–1.66)	1.20 (0.80–1.78)	1.06 (0.64–1.75)	0.71	1.31 (0.79–2.46)	0.40
SFA
Median, g/day	12.9	18.6	23.3	28.7	37.9
(% energy)	(11)	(12)	(14)	(15)	(17)
Cases	84	83	85	86	94
HR (95% CI)b	1.00	0.93 (0.66–1.30)	0.90 (0.60–1.35)	0.88 (0.54–1.45)	0.93 (0.56–1.88)	0.86	0.81 (0.53–1.23)	0.32
Breast cancer after the age 50 yearsd
Total fat
Median, g/day	30.8	42.8	52.4	63.0	80.2
(% energy)	(27)	(29)	(31)	(32)	(34)
Cases	130	115	111	107	79
HR (95% CI)b	1.00	0.91 (0.70–1.20)	0.93 (0.69–1.27)	0.93 (0.65–1.33)	0.76 (0.47–1.22)	0.34	1.01 (0.93–1.11)	0.77
MUFA
Median, g/day	10.4	14.4	17.5	20.9	26.4
(% energy)	(9)	(10)	(10)	(11)	(11)
Cases	130	118	112	105	77
HR (95% CI)b	1.00	0.86 (0.64–1.15)	0.79 (0.55–1.15)	0.73 (0.46–1.17)	0.45 (0.25–0.99)	0.01	0.55 (0.28–1.09)	0.09
PUFA
Median, g/day	4.3	6.0	7.3	8.7	11.2
(% energy)	(3.6)	(4.0)	(4.3)	(4.5)	(4.9)
Cases	131	121	97	108	85
HR (95% CI)b	1.00	0.89 (0.68–1.15)	0.72 (0.53–0.98)	0.76 (0.54–1.06)	0.54 (0.35–0.85)	0.08	0.58 (0.32–1.05)	0.06
SFA
Median, g/day	12.9	18.6	23.3	28.8	37.6
(% energy)	(11)	(13)	(14)	(15)	(16)
Cases	123	115	113	102	89
HR (95% CI)b	1.00	1.03 (0.77–1.39)	1.16 (0.80–1.67)	1.15 (0.72–1.83)	1.29 (0.66–2.50)	0.44	1.45 (0.99–2.12)	0.06

% energy=percent energy of total energy intake.

^an=44 569; 974 breast cancer cases.

^bAdjusted for education, parity, age at menarche, use of oral contraceptives, age at first birth by parity, first-degree relative with breast cancer, non-alcohol total energy intake, total fat intake, BMI and alcohol intake. Attained age was utilised as time scale.

^cn=44 569; 432 breast cancer cases.

^dn=30 132; 542 breast cancer cases.