Table 3. Number of deaths (N) and mortality rates (R) per million person–years at risk by age and diagnostic group at ages 13–29 years in England and Wales, 1981–2005.

		13–14		15–19		20–24		25–29		P-value	PCYAa
Main group	Subgroup	N	R	N	R	N	R	N	R	Heter.	Value	(95% CI)
Lip, oral cavity and pharynx		19	0.6	68	0.8	88	1.0	117	1.3	0.0006	5.52*	(2.82,8.30)
Digestive organs		26	0.8	147	1.7	358	4.0	805	8.7	<0.0001	18.71*	(17.47,19.97)
	Colorectal	8	0.2	46	0.5	131	1.4	321	3.5	<0.0001	21.97*	(18.19,25.88)
	Liver	14	0.4	66	0.8	99	1.1	133	1.4	<0.0001	8.03*	(5.87,10.25)
	Other sites in GI tract	4	0.1	35	0.4	128	1.4	351	3.8	<0.0001	29.03*	(24.33,33.90)
Respiratory and intrathoracic organs		10	0.3	48	0.6	111	1.2	250	2.7	<0.0001	17.66*	(14.82,20.57)
Bone and articular cartilage		199	6.0	673	7.8	503	5.6	250	2.7	<0.0001	−7.63*	(−10.43,−4.75)
Melanoma of skin		7	0.2	60	0.7	239	2.6	478	5.2	<0.0001	27.63*	(21.44,34.13)
Mesothelial and soft tissue		71	2.1	282	3.3	361	4.0	368	4.0	<0.0001	3.75*	(1.63,5.91)
Breast		0	0.0	9	0.1	72	0.8	639	6.9	<0.0001	49.81*	(44.42,55.42)
Genitourinary organs		32	1.0	186	2.2	562	6.2	1379	14.9	<0.0001	22.21*	(20.42,24.02)
	Cervix	0	0.0	6	0.1	123	2.7	644	13.9	<0.0001	54.12*	(47.02,61.56)
	Ovary	11	0.7	58	1.4	124	2.8	217	4.7	<0.0001	14.67*	(11.83,17.59)
	Testis	2	0.1	73	1.7	216	4.8	330	7.1	<0.0001	26.51*	(17.88,35.77)
	Other sites	19	0.6	49	0.6	99	1.1	188	2.0	<0.0001	11.85*	(8.72,15.07)
Malignant neoplasms of CNS		260	7.8	570	6.6	721	8.0	1048	11.3	<0.0001	3.85*	(2.03,5.71)
Thyroid and other endocrine glands		29	0.9	82	0.9	83	0.9	95	1.0	0.8513	0.91	(−1.64,3.52)
Malignant neoplasms of lymphoid, haematopoietic and related tissue		543	16.2	1864	21.6	2129	23.5	2484	26.8	<0.0001	3.13*	(2.05,4.23)
	Lymphoid leukaemia	261	7.8	768	8.9	536	5.9	363	3.9	<0.0001	−6.36*	(−8.17,−4.52)
	Myeloid and monocytic leukaemia	147	4.4	478	5.5	616	6.8	757	8.2	<0.0001	4.50*	(3.75,5.27)
	Hodgkin's lymphoma	20	0.6	207	2.4	451	5.0	600	6.5	<0.0001	15.88*	(11.04,20.94)
	Non-Hodgkin's lymphoma	78	2.3	340	3.9	466	5.2	701	7.6	<0.0001	7.97*	(6.52,9.43)
	Other and unspecified lympho-haematopoietic	37	1.1	71	0.8	60	0.7	63	0.7	0.0803	−2.12	(−6.45,2.41)
Other malignant neoplasms		27	0.8	135	1.6	218	2.4	446	4.8	<0.0001	13.80*	(10.97,16.69)
Benign neoplasms and neoplasms of uncertain behaviour		89	2.7	199	2.3	250	2.8	337	3.6	<0.0001	3.36*	(2.02,4.72)
	Eye, brain, and other parts of CNS	42	1.3	78	0.9	105	1.2	163	1.8	<0.0001	4.58*	(1.19,8.08)
	Other sites	47	1.4	121	1.4	145	1.6	174	1.9	0.0526	2.41*	(0.91,3.93)
All groups		1312	39.2	4323	50.0	5695	63.0	8696	93.8	<0.0001	6.53*	(5.80,7.26)

^aPercentage change per year of age.

^*Denotes significance at the 5% level.