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. 2007 Jun 26;97(2):210–217. doi: 10.1038/sj.bjc.6603857

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Copyright © 2007 Cancer Research UK

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In vivo tumorigenicity of 10⁶ unmodified Neuro-2A cells when coinjected subcutaneously with 10⁶ unmodified AJ3.1, 10⁶ cytokine-transfected AJ3.1 cells or 10⁶ cytokine-transfected Neuro-2A in syngeneic mice (n=6 per group). In total, 83% of mice in the therapeutic groups did not develop tumours and remained tumour free for over 40 days, while control mice receiving unmodified AJ3.1+Neuro-2A or Neuro-2A only all developed aggressive tumours within 11 days.