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. 2007 Jun 19;97(2):267–274. doi: 10.1038/sj.bjc.6603852

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Copyright © 2007 Cancer Research UK

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Methylation status of S100 genes in primary medulloblastomas and the normal cerebellum. Analysis of methylation at CpG residues within the promoter-associated CpG islands of S100A2, S100A6 and S100A10 and the first intron of S100A4, is shown in normal cerebella and selected medulloblastoma primary tumours, determined by bisulphite sequencing and estimation of relative peak heights (as described in Figure 2). Filled circles, >75% methylation; half-filled circles, 25–75% methylation; empty circles, <25% methylation.