Table 1. Correlation between MK expression and clinicopathologic factors in pancreatic head carcinoma.
|
MK expression
|
||||
|---|---|---|---|---|
| Total n=75 | Positive n=40 (53.3%) | Negative n=35 (46.7%) | P-values | |
| Age (years) | ||||
| Mean±s.d. | 67.4±8.9 | 64.9±9.9 | 0.2648 | |
| Gender | ||||
| Male | 50 (66.7) | 23 (57.5) | 27 (77.1) | 0.0718 |
| Female | 25 (33.3) | 17 (42.5) | 8 (22.9) | |
| Histology | ||||
| Well | 29 (38.7) | 14 (35.0) | 15 (42.9) | 0.2318 |
| Moderately | 43 (57.3) | 23 (57.5) | 20 (57.1) | |
| Poor | 3 (4.0) | 3 (7.5) | 0 (0.0) | |
| pT | ||||
| pT1 | 3 (4.0) | 1 (2.5) | 2 (5.7) | 0.3699 |
| pT2 | 5 (6.7) | 1 (2.5) | 4 (11.4) | |
| pT3 | 59 (78.7) | 33 (82.5) | 26 (74.3) | |
| pT4 | 8 (10.7) | 5 (12.5) | 3 (8.6) | |
| pN | ||||
| Negative | 28 (37.3) | 14 (35.0) | 14 (40.0) | 0.6552 |
| Positive | 47 (62.7) | 26 (65.0) | 21 (60.0) | |
| Liver metastasis | ||||
| Negative | 47 (62.7) | 20 (50.0) | 27 (77.1) | 0.0153 |
| Positive | 28 (37.3) | 20 (50.0) | 8 (22.9) | |
| pStage | ||||
| I | 6 (8.0) | 1 (2.5) | 5 (14.3) | 0.3651 |
| IIA | 21 (28.0) | 13 (32.5) | 8 (22.9) | |
| IIB | 38 (50.7) | 20 (50.0) | 18 (51.4) | |
| III | 6 (8.0) | 4 (10.0) | 2 (5.7) | |
| IV | 4 (5.3) | 2 (5.0) | 2 (5.7) | |
| Lymphatic invasion | ||||
| Negative | 9 (12.0) | 4 (10.0) | 5 (14.3) | 0.5688 |
| Positive | 66 (88.0) | 36 (90.0) | 30 (85.7) | |
| Venous invasion | ||||
| Negative | 19 (25.3) | 5 (12.5) | 14 (40.0) | 0.0063 |
| Positive | 56 (74.7) | 35 (87.5) | 21 (60.0) | |
| Microvessel density | ||||
| Low grade | 33 (44.0) | 11 (27.5) | 22 (62.9) | 0.0021 |
| High grade | 42 (56.0) | 29 (72.5) | 13 (37.1) | |
MK=midkine; s.d.=standard deviation.