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. 2007 Jul 31;97(3):368–377. doi: 10.1038/sj.bjc.6603884

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Copyright © 2007 Cancer Research UK

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Induction of c-MET phosphorylation by HGF. HGF induction of tyrosine phosphorylation of c-MET at the phosphoepitopes p-MET [pY1003], the juxtamembrane c-CBL-binding site, and p-MET [pY1230/1234/1235], the cytoplasmic catalytic kinase domain autophosphorylation site as confirmed by immunoblotting is shown quantitatively here.