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. 2007 Jul 10;97(4):494–501. doi: 10.1038/sj.bjc.6603885

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Copyright © 2007 Cancer Research UK

This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.

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Synergistic antiproliferative effects of cetuximab and trastuzumab for oesophageal SCC cell lines. The oesophageal SCC lines, TE3 (HER-2 low and EGFR high) and TE5 (HER-2 moderate and EGFR moderate), were analysed by the MTT assay in various dose combinations of cetuximab and trastuzumab. The inhibition of proliferation was shown as % cell growth inhibition induced by cetuximab and/or trastuzumab in comparison with that induced by control mAb.