Table 2. Grade III/IV toxicity in relation to chemotherapy dose level during chemoradiotherapy in 31 patients that completed treatment as planned.
Dose level | Cisplatin dose (mg m−2) | Capecitabine dose (mg m−2) | n | Neutropaenia | Thrombocytopaenia | Nausea | Hand-foot syndrome | Dysphagia | Fatigue |
---|---|---|---|---|---|---|---|---|---|
I | 3 | 250 | 3 | ||||||
II | 4 | 250 | 3 | ||||||
III | 4 | 350 | 3 | ||||||
IV | 4 | 500 | 3 | 1 | 1 | ||||
V | 5 | 575 | 6 | 1a | 1 | ||||
VI | 5 | 650 | 8 | 1 | 1 | ||||
VII | 6 | 650 | 5 | 2 | 1 | 1 |
Grade IV.