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. 2007 Sep 11;97(6):712–716. doi: 10.1038/sj.bjc.6603965

Table 2. Grade III/IV toxicity in relation to chemotherapy dose level during chemoradiotherapy in 31 patients that completed treatment as planned.

Dose level Cisplatin dose (mg m−2) Capecitabine dose (mg m−2) n Neutropaenia Thrombocytopaenia Nausea Hand-foot syndrome Dysphagia Fatigue
I 3 250 3            
II 4 250 3            
III 4 350 3            
IV 4 500 3 1     1    
V 5 575 6 1a       1  
VI 5 650 8 1   1      
VII 6 650 5   2 1     1
a

Grade IV.