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. 2007 Aug 28;97(6):792–801. doi: 10.1038/sj.bjc.6603948

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Copyright © 2007 Cancer Research UK

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Grp94 mRNA expression status in primary oral squamous cell carcinomas (OSCCs) and OSCC-derived cell lines. (A) Comparison of Grp94 mRNA expression levels between Grp94-positive and Grp94-negative cases classified by immunohistochemical analysis. There is a significant difference in the Grp94 mRNA expression levels between the negative and positive cases (P<0.001, Mann–Whitney's U-test). (B) Quantification of mRNA levels in OSCC-derived cell lines by qRT–PCR analysis. Significant upregulation of Grp94 mRNA expression is seen in all OSCC-derived cell lines examined compared to normal oral epithelium. Data are expressed as the means±s.d.