Table 2. Childhood leukaemia mortality rate per million person-years by sex and age, England and Wales, 1911–2000.

	Period of death																		Average quinquennial change (1971–2000)
	1911–1915	1916–1920	1921–1925	1926–1930	1931–1935	1936–1940	1941–1945	1946–1950	1951–1955	1956–1960	1961–1965	1966–1970	1971–1975	1976–1980	1981–1985	1986–1990	1991–1995	1996–2000	Time trenda	95% confidence interval
All	8.4	8.0	10.2	15.2	18.4	22.3	25.5	30.4	34.1	34.7	32.9	29.7	26.4	22.0	17.1	14.0	10.9	10.3	−3.8	−3.8	−3.8
Sex
Male	10.3	9.8	12.5	18.0	20.4	26.0	30.4	33.6	37.0	38.3	36.1	32.4	29.3	26.8	19.6	15.4	13.5	11.6	−3.9	−3.9	−3.9
Female	6.4	6.2	8.0	12.3	16.3	19.2	20.5	27.2	31.9	30.9	29.4	27.0	23.3	17.0	14.6	12.6	8.1	8.9	−3.2	−3.2	−3.2
Age (years)
<1	9.9	10.8	11.6	17.4	19.7	28.4	29.4	25.1	29.0	23.2	24.8	19.4	18.8	13.8	12.7	8.9	9.5	6.4	−2.2	−3.0	−1.3
1–4	11.5	10.2	13.4	21.9	25.5	33.6	36.0	46.8	51.8	48.5	43.8	37.9	30.6	21.7	16.4	14.8	9.4	10.6	−3.7	−4.2	−3.1
5–9	7.5	7.0	9.5	12.6	16.2	18.4	22.1	26.3	29.7	35.6	34.7	30.2	30.9	27.2	18.7	13.6	12.2	10.0	−4.1	−4.6	−3.7
10–14	5.5	6.1	7.3	10.3	12.8	13.0	17.2	19.1	21.3	22.0	21.3	23.4	18.9	18.9	17.4	15.0	11.2	11.3	−1.8	−2.3	−1.4

^aAverage quinquennial change in the mortality rate per million person-years between 1971–1975 and 1996–2000.

Mortality rates are age-standardised to the world standard population.