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. 2007 Oct 2;97(7):934–940. doi: 10.1038/sj.bjc.6603985

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Copyright © 2007 Cancer Research UK

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ZD6474 reverses P-gp-mediated resistance. P-gp-negative MCF-7 cells or P-gp-positive MCF-7/adriamycin (ADR) and KBV200 cells were treated with (ADR, docetaxel, or vinorelbine (VNR) in the presence or absence of ZD6474 for different periods of time, and the cell proliferation was determined by the SRB assay. Each point represents the mean±s.d. for three determinations.