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. 2007 Sep 11;97(7):957–963. doi: 10.1038/sj.bjc.6603963

Figure 2.

Figure 2

Hierarchical clustering analysis of global matrix metalloproteinases (MMPs)/tissular inhibitors of metalloproteinases (TIMPs) expressions in the different cell types of breast cancer as measured by immunohistochemistry on tissue microarray (TMA). Graphical representation of hierarchical clustering results in tumour cells (A), fibroblasts (B) and mononuclear inflammatory cells (C). Rows, tumoural samples; columns, MMPs/TIMPs. Protein expressions are depicted according to a color scale: red, positive staining; green, negative staining; grey, missing data. No major clusters of tumours are shown in tumour cells and fibroblasts. Two major clusters of tumours (1 and 2) are shown in mononuclear inflammatory cells.