Table 5. Cox proportional hazard estimation of overall survival in ovarian adenocarcinomas.
|
95% confidence limits for the hazard ratio
|
||||
|---|---|---|---|---|
| Covariate | P | Hazard ratio | Lower | Upper |
| A1 a | ||||
| MCM-2 | 0.001 | 1.058 | 1.023 | 1.093 |
| Stage (I/II vs III/IV) | 0.045 | 11.16 | 1.06 | 117.52 |
| B1 b | ||||
| MCM-5 | 0.036 | 1.027 | 1.001 | 1.053 |
| A2 c | ||||
| MCM-2 | <0.0001 | 1.116 | 1.049 | 1.187 |
| p21WAF1 | 0.028 | 0.621 | 0.406 | 0.949 |
| B2 d | ||||
| MCM-5 | 0.022 | 1.043 | 1.006 | 1.082 |
a
A1 model included the conventional clinicopathologic parameters and MCM-2LI.
b
B1 model included the conventional clinicopathologic parameters and MCM-5LI.
c
A2 model included the conventional clinicopathologic parameters, MCM-2LI, Ki-67LI and the cell cycle regulators.
d
B2 model included the conventional clinicopathologic parameters, MCM-5LI, Ki-67LI and the cell cycle regulators.