Table 1. The relationship between clinicopathological characteristics, the systemic inflammatory response and survival in patients with colorectal cancer.
Primary operable (n=149) | Synchronous unresectable (n=84) | P-value | |
---|---|---|---|
Age (<65/65–74/>75 years) | 48/52/49 | 34/27/23 | 0.215 |
Sex (male/female) | 81/68 | 48/36 | 0.683 |
Deprivation (1–2/3–5/6–7)a | 5/66/78 | 7/33/44 | 0.981 |
Tumour site (colon/rectum) | 83/66 | 52/32 | 0.358 |
TNM Stage (I/II/III/IV) | 22/62/65/0 | 0/0/0/84 | <0.001 |
White cell count (<8.5/8.5–11/>11 × 109 l−1) | 82/40/17 | 30/27/27 | <0.001 |
Neutrophil count (<7.5/>7.5 × 109 l−1) | 129/20 | 49/35 | <0.001 |
Lymphocyte count (>3.0/1.0–3.0/<1.0 × 109 l−1) | 7/131/11 | 2/66/16 | 0.008 |
Neutrophil/lymphocyte ratio (<5/>5) | 124/25 | 48/36 | <0.001 |
Monocyte count (<0.9/>0.9 × 109 l−1) | 132/17 | 61/23 | 0.002 |
Platelet count (<400/>400 × 103 l−1) | 117/32 | 55/27 | 0.057 |
C-reactive protein (<10/>10 mg l−1) | 88/61 | 17/64 | <0.001 |
Albumin (>35/<35 g l−1) | 135/14 | 55/29 | <0.001 |
MGPS (0/1/2) | 88/48/13 | 17/44/23 | <0.001 |
Alive | 104 | 13 | |
Dead | |||
Cancer | 20 | 71 | |
Non-cancer | 25 | 0 | <0.001 |
TNM=tumour, node, metastases; mGPS=modified Glasgow Prognostic Score.
Individual deprivation categories were used in the statistical analysis.