Table 3. Correlation between VEGF-C/VEGFR-3 and clinicopathological factors.
| Clinicopathological factors | No. of patients | VEGF-C/VEGFR-3 | P-value |
|---|---|---|---|
| Age | |||
| 70> | 40 | 2.24±2.89 | 0.58 |
| 70⩽ | 34 | 2.66±3.57 | |
| Gender | |||
| Male | 54 | 2.88±3.57 | 0.006 |
| Female | 20 | 1.24±1.38 | |
| T | |||
| 1 | 28 | 1.79±2.22 | 0.27 |
| 2 | 32 | 2.72±3.84 | |
| N | |||
| (−) | 48 | 1.77±2.44 | 0.03 |
| (+) | 26 | 3.66±4.05 | |
| Stage | |||
| I, II | 51 | 2.19±2.84 | 0.34 |
| III, IV | 23 | 2.97±3.91 | |
| Histological type | |||
| Adenocarcinoma | 39 | 1.70±2.02 | 0.04 |
| Squamous cell ca | 32 | 3.40±3.40 | |
| Differentiation | |||
| Adenocarcinoma | |||
| Well | 16 | 1.08±1.12 | 0.08 |
| Mod or Poor | 23 | 2.12±2.39 | |
| Squamous cell ca | |||
| Well | 6 | 1.58±0.92 | 0.24 |
| Mod or Poor | 26 | 3.82±4.49 | |
VEGF-C: vascular endothelial growth factor-C;
VEGFR-3: vascular endothelial growth factor receptor-3.