Table 2. Multivariate survival analysis of pretreatment clinical factors.

Risk factors	Categories compared	P-value	Risk ratio	95% CI
Grade	G1/G2 vs G3/G4	0.003	3.923	1.608–9.573
CRP	<0.8 vs ⩾0.8 mg dl−1	0.034	2.721	1.080–6.858
Metastasectomy	Yes vs no	0.010	0.297	0.118–0.749
LDH	<300 vs >300 U l−1	0.035	3.037	1.080–8.540

CI=confidence interval; CRP=C-reactive protein; LDH=lactate dehydrogenase.