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. 2006 Aug 22;95(6):735–743. doi: 10.1038/sj.bjc.6603299

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Copyright © 2006 Cancer Research UK

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Association between hypoxia, TILs apoptosis and EMAP-II in CRC in vivo. (A) Immunohistochemical staining of a moderately differentiated adenocarcinoma of the colon with polyclonal anti-CA IX antibody. There is a strong membranous and cytoplasmic staining within the malignant epithelial cells (original magnification × 200). (B) TILs in tumourous tissues were strongly reactive with antiactive caspase-3 antibody (original magnification × 400). (C) Apoptotic TILs immunostained against cleaved PARP antibody (original magnification × 400). (D) Strong brown cytoplasmic staining of malignant epithelial cells in the tumour with EMAP-II (original magnification × 200).

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