Table 2. Association between anaemia during pregnancy (haemoglobin concentration <11 g dl−1) and infant leukaemia.
Odds ratio (95% CI) unadjusted | Adjusteda ODDS ratio (95% CI) | |
---|---|---|
Overall leukaemia (n=178) | 0.85 (0.53–1.37) | 0.93 (0.57–1.53) |
AML (n=63) | 0.64 (0.32–1.30) | 0.67 (0.32–1.37) |
ALL (n=115) | 0.98 (0.58–1.66) | 1.14 (0.65–2.01) |
MLL+ (n=92) | 0.77 (0.42–1.40) | 0.88 (0.47–1.63) |
MLL− (n=62) | 0.88 (0.45–1.73) | 0.96 (0.48–1.91) |
AML/MLL+ (n=21) | 0.46 (0.13–1.64) | 0.57 (0.16–2.07) |
AML/MLL− (n=29) | 0.72 (0.28–1.88) | 0.70 (0.26–1.89) |
ALL/MLL+ (n=71) | 0.87 (0.46–1.65) | 0.98 (0.50–1.91) |
ALL/MLL− (n=33) | 1.04 (0.45–2.39) | 1.33 (0.55–3.24) |
Association is adjusted for maternal race (white, black, Hispanic and other) and birth order (number of live births prior to index child). Maternal education (⩽HS, >HS <college grad, ⩾college grad), household income (<$30 000, $30 000–$75 000, >$75 000), maternal age at time of index child's birth, child gender, smoking during pregnancy and birth weight were not significant confounders and are not included in the adjusted model.