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. 2006 Oct 3;95(9):1202–1211. doi: 10.1038/sj.bjc.6603369

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Copyright © 2006 Cancer Research UK

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Cytotoxicity of EZH2-specific cytotoxic T-cell clones 691, 696 and 480 derived from normal donor 001 and HCC patient 002 against (A) HLA-A0201-matched primary human fibroblasts infected with recombinant adenoviruses (either RAdEZH2 or RAdControl) and (B) the HLA-A0201-positive breast carcinoma cell line MCF7. Chromium release assays employed 2.5 × 10³ target cells well⁻¹. Effector : target cell ratios and additions of either IFN-γ or monoclonal antibody BB7.2 are indicated on individual graphs. The results shown are means of triplicate wells and standard errors were less than 10%.