Table 1. Characteristics of seven patients with SPC following chemoradiation.
Type of SPC | First to second cancer (years) | Smoking (pack-year) | Chemo | RT field | First symptom | Treatment of SPC | Survival after SPC (years) |
---|---|---|---|---|---|---|---|
Gall bladder | 2.5 | 100 | DP | Outside | Abdominal pain | Curative operation | 1.2 (died of SPC) |
Oesophagus | 4.1 | 30 | FP | Outside | None | Curative chemo RT | 7.2 (alive) |
Lung (adeno) | 5.9 | 30 | DP | Outside | None | Curative operation | 1.6 (alive) |
Oesophagus | 8.3 | 50 | FP | Inside | Dysphagia | Palliation | 0.35 (died of SPC) |
Lung (adeno) | 8.3 | 68* | FP | Outside | None | Curative operation | 1.5 (alive) |
Bile duct | 8.7 | 40 | FP | Outside | Jaundice | Palliative chemo | 0.79 (died of SPC) |
Lung (small) | 9.5 | 75 | FP | Outside | None | Chemo | 1.1 (alive) |
Adeno=adenocarcinoma; chemo=chemotherapy; DP=docetaxel and cisplatin; FP=5-fluorouracil and cisplatin; RT=radiation; small=small-cell carcinoma; SPC=second primary cancer;
The number of 68 was the value at the time of diagnosis of initial NSCLC and this patient had continued smoking as SPC was found.