Table 2. CI at Fa of 0.5 and 0.9 of YM529 in combination with cisplatin and paclitaxel in bladder cancer cells.

Cell	Agents	CI at Fa 0.5	Effect	CI at Fa 0.9	Effect
KU-7
	Cisplatin	1.107	Additive	0.696	Synergistic
	Paclitaxel	1.066	Additive	0.914	Synergistic
RT112
	Cisplatin	0.736	Synergistic	0.794	Synergistic
	Paclitaxel	0.844	Additive	1.227	Additive
UM-UC-3
	Cisplatin	0.878	Synergistic	1.044	Additive
	Paclitaxel	0.555	Synergistic	1.135	Additive

CI=Combination indexes; Fa=fraction affected.