Table 5. Counts of G382D and Y165C mutations reported in the published data and GRR.

	G382D		Y165C
Study	Cases	Controls	Cases	Controls
(Croitoru et al, 2004)	4/21/1197	0/17/1234	2/8/1197	0/4/1234
(Farrington et al, 2005)	8/31/2160	0/20/1794	0/14/2160	0/8/1794
(Peterlongo et al, 2005)	1/2/549	0/5/911	0/2/549	0/2/911
(Fleischmann et al, 2004)	1/4/351	0/0/97	0/1/351	0/0/97
(Kambara et al, 2004)	0/2/90	0/0/52	0/0/90	0/1/52
(Wang et al, 2004)	0/5/432	0/2/309	1/5/432	0/2/309
(Enholm et al, 2003)	1/4/994	0/0/424	0/1/994	0/0/424
(Zhou et al, 2005)	0/2/432	0/1/466	0/4/432	0/2/466
Current replication study	2/15/905	0/14/825	2/3/905	0/6/825
Overall numbers	17/86/7110	0/59/6112	5/38/7110	0/25/6112
GRR (MM/WM/WW)	103.63/1.26/1		168.82/1.31/1
GRR 95% CI (MM/WM/WW)	(55.26–188.61)/(0.96–1.68)/(1.00–1.00)		(48.77–438.31)/(0.86–2.06)/(1.00–1.00)

CI=confidence interval; GRR=genotype relative risk.