Table 3. Lipide profile: mean values (±s.d.) on tamoxifen and exemestane therapy.
|
Tamoxifen
|
||||||
|---|---|---|---|---|---|---|
| Exemestane | Baseline | 6th month | 12th month | Baseline | 6th month | 12th month |
| TC (mg dl−1) | 215.12±10.01 (CI:211.34–218.90) | 216.23±10.44 (CI:212.29–220.17) | 215.32±11.21 (CI:211.09–219.55) | 215.68±9.31 (CI:212.23–219.13) | 224.27±13.33 (CI:219.33–229.21) | 224.17±12.83 (CI:219.42–228.92) |
| HDL-C (mg dl−1) | 58.62±6.17 (CI:56.29–60.95) | 58.22±8.77 (CI:54.91–61.53) | 57.98±8.01 (CI:54.96–61.00) | 58.07±6.40 (CI:55.7–60.44) | 53.41±8.10 (CI:50.41–56.41) | 51.20±8.08* (CI:48.21–54.19) |
| LDL-C (mg dl−1) | 131.15±14.51 (CI:125–68–136.62) | 133.56±19.10 (CI:126.36–140.76) | 132.31±19.24 (CI:125.05–139.57) | 130.91±15.10 (CI:125.32–136.50) | 149.8±17.18* (CI:143.44–156.16) | 152.81±18.12**# (CI:146.10–159.52) |
| TG (mg dl−1) | 124.87±46.1 (CI:107.48–142.26) | 119.30±47.81 (CI:101.27–137.33) | 127.63±40.60 (CI:112.32–142.94) | 124.11±58.27 (CI:102.53–145.69) | 107.21±64.30* (CI:83.39–131.03) | 101.04±43.65** (CI:84.87–117.21) |
CI=confidence interval; HDL-C=high-density lipoprotein cholesterol; LDL-C=low-density lipoprotein cholesterol; TC=total cholesterol; TG=total triglycerides.
*
P<0.05,
**
P<0.01 vs baseline values; #P<0.05 between groups.