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. 2006 Jul 4;95(3):378–384. doi: 10.1038/sj.bjc.6603229

Table 3. OR of HL for alcohol drinking and age groupa.

  Controls n=1755 All HL, n=224
Nodular sclerosis HL, n=137
  n n ORb 95% CI n ORb 95% CI
Subjects overall
Never regular drinker 876 141     88    
 Ever regular drinker 866 81 0.61 (0.43–0.87) 47 0.58 (0.37–0.92)
  Beer drinker 507 57 0.63 (0.41–0.94) 34 0.60 (0.35–1.02)
  Wine drinker 645 43 0.57 (0.37–0.88) 23 0.60 (0.34–1.06)
  Spirits drinker 284 42 0.78 (0.50–1.22) 25 0.68 (0.38–1.20)
 
Subjects <35 years old
Never regular drinker* 119 83     61    
 Ever regular drinker 96 40 0.63 (0.37–1.09) 28 0.62 (0.33–1.16)
  Beer drinker 69 33 0.76 (0.41–1.39) 23 0.78 (0.38–1.59)
  Wine drinker 41 12 0.49 (0.22–1.10) 7 0.44 (0.16–1.19)
  Spirits drinker 46 24 0.78 (0.41–1.51) 17 0.70 (0.33–1.50)
 
Monthly consumption (g)
 ⩽66 6 3 0.79 (0.18–3.51) 2 1.13 (0.18–7.17)
 >66 and ⩽341 13 4 0.56 (0.16–2.01) 2 0.46 (0.09–2.50)
 >341 24 9 0.72 (0.27–1.89) 7 0.91 (0.29–2.80)
P trendc       0.17     0.44
 
Age at start (years)
 ≥18 38 19 0.75 (0.38–1.47) 11 0.57 (0.25–1.30)
 ≥16 and <18 35 13 0.50 (0.23–1.12) 10 0.54 (0.22–1.33)
 <16 22 6 0.46 (0.17–1.26) 6 0.76 (0.26–2.22)
P trendc       0.52     0.64
 
Duration (years)
 ⩽7 35 15 0.57 (0.27–1.19) 13 0.62 (0.28–1.39)
 >7 and ⩽13 35 12 0.47 (0.21–1.05) 6 0.28 (0.10–0.81)
 >13 25 11 1.01 (0.40–2.56) 8 1.57 (0.52–4.75)
P trendc       0.03     0.18
 
Lifetime consumption (kg)
 <16 27 8 0.44 (0.18–1.06) 4 0.29 (0.09–0.92)
 ≥16 and <61 31 14 0.66 (0.31–1.41) 10 0.69 (0.29–1.65)
 ≥61 36 16 0.76 (0.35–1.64) 13 0.96 (0.40–2.33)
P trendc       0.07     0.16
 
Subjects ≥35 years old
Never regular drinker** 757 58     27    
 Ever regular drinker 770 41 0.58 (0.35–0.94) 19 0.52 (0.26–1.04)
  Beer drinker 438 24 0.51 (0.28–0.92) 11 0.42 (0.18–0.98)
  Wine drinker 604 31 0.58 (0.34–1.01) 16 0.67 (0.32–1.42)
  Spirits drinker 238 18 0.71 (0.38–1.36) 8 0.57 (0.23–1.43)
 
Monthly consumption (g)
 ⩽215 121 5 0.52 (0.20–1.38) 3 0.58 (0.16–2.08)
 >215 and ⩽734 249 13 0.63 (0.32–1.24) 7 0.64 (0.25–1.60)
 >734 274 19 0.66 (0.35–1.26) 7 0.47 (0.18–1.25)
P trendc       0.09     0.40
 
Age at start (years)
 >22 216 12 0.72 (0.36–1.42) 7 0.82 (0.33–2.05)
 >18 and ⩽22 203 7 0.44 (0.19–1.04) 3 0.41 (0.12–1.48)
 ⩽18 320 22 0.63 (0.34–1.15) 9 0.45 (0.18–1.10)
P trendc       0.88     0.31
 
Duration (years)
 ⩽29 238 20 0.53 (0.29–0.97) 10 0.47 (0.20–1.11)
 >29 and ⩽44 266 15 0.73 (0.37–1.44) 5 0.53 (0.18–1.57)
 >44 253 6 0.51 (0.19–1.38) 4 0.76 (0.21–2.77)
P trendc       0.60     0.40
 
Lifetime consumption (kg)
 <143 221 16 0.72 (0.39–1.33) 9 0.76 (0.33–1.76)
 ≥143 and <425 259 14 0.55 (0.28–1.09) 5 0.38 (0.13–1.09)
 ≥425 259 11 0.50 (0.23–1.07) 5 0.44 (0.15–1.33)
P trendc       0.07     0.23

CI=confidence interval; HL=Hodgkin's lymphoma; OR=odds ratio.

*

Reference category for all alcohol variables among subjects <35 years old.

**

Reference category for all alcohol variables among subjects ≥35 years old.

a

Excluding data from Germany.

b

Adjusted for age, sex, educational level, smoking status and centre.

c

P trend using ever-regular drinkers only (excludes never-regular drinkers) and adjusted for the other alcohol variables in the table.