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. 2006 Aug 1;95(4):506–514. doi: 10.1038/sj.bjc.6603285

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Copyright © 2006 Cancer Research UK

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Changes of biochemical marker levels in patients with primary breast carcinoma who developed or remained free of bone metastases during a 3 years follow-up. The bars represent the changes of levels between the follow-up and the initial visits divided by the duration of follow-up and expressed as percentage of the initial value. The actual P-values indicated on the figure refers to the comparison of the percentage changes between the two groups. ^*P<0.05, ^**P<0.01, ^***P<0.001 at follow-up vs baseline in each group separately.