Table 1. Details of SNPs used in the analyses.

Gene	Label	db SNPa	MAFb	Location	Codon number	Amino acidc
CAT	CAT-01	rs1001179	0.22	Regulatory	0
CAT	CAT-03	rs769217	0.22	Silent	389	D>D
CAT	CAT-04	rs511895	0.42	Intronic	0
CAT	CAT-05	rs7104301	0.26	Regulatory	0
CAT	CAT-08	rs1049982	0.32	5′UTRd	0
GPX1	GPx1-01	rs3448	0.25	Intergenic
GPX4	GPx4-02	rs713041	0.46	3′UTR	0
GPX4	GPx4-04	rs4807542	0.16	Silent	12	P>P
GPX4	GPX4-06	rs757229	0.46	Intergenic	0
GSR	GSR-01	rs1002149	0.16	Regulatory	0
GSR	GSR-07	rs4628224	0.19	Intronic	0
GSR	GSR-12	rs8190924	0.05	Intronic	0
GSR	GSR-14	rs2978663	0.37	Intronic	0
GSR	GSR-16	rs8191009	0.20	Intronic	0
GSR	GSR-18	rs3926402	0.39	Intronic	0
GSR	GSR-19	rs2911678	0.22	Intronic	0
SOD1	SOD1-01	rs4998557	0.12	Intronic	0
SOD1	SOD1-02	rs202445	0.17	Regulatory	0
SOD1	SOD1-03	rs2070424	0.07	Intronic
SOD2	SOD2-02	rs1799725	0.49	Missense	16	V>A
SOD2	SOD2-05	rs2842958	0.21	Intronic	0
TXN	TRX1-02	rs1410051	0.24	Intronic	0
TXN	TRX1-03	rs4135168	0.26	Intronic	0
TXN	TRX1-05	rs4135192	0.33	Intronic	0
TXN	TRX1-06	rs2418076	0.27	Intronic	0
TXN	TRX1-07	rs4135208	0.33	Intronic	0
TXN	TRX1-08	rs4135211	0.07	Intronic	0
TXN	TRX1-09	rs4135225	0.33	Intronic	0
TXN	TRX1-10	rs2776	0.50	3′UTR	0
TXN	TRX1-11	rs2301241	0.41	5′UTR	0
TXN	TRX1-12	rs4135165	0.09	Intronic	0
TXN	TRX1-13	rs4135172	0.08	Intronic	0
TXN	TRX1-14	rs4135179	0.23	Intronic	0
TXN	TRX1-15	rs4135215	0.16	Intronic	0
TXN	TRX1-16	rs4135221	0.13	Intronic	0
TXN2	TRX2-01	rs2281082	0.19	Intronic	0
TXN2	TRX2-03	rs8139906	0.18	Intronic	0
TXN2	TRX2-04	rs8140110	0.09	Intronic	0
TXNRD1	TRXR1-01	rs4964778	0.18	Intronic	0
TXNRD1	TRXR1-02	rs4964779	0.12	Intronic	0
TXNRD1	TRXR1-03	rs4564401	0.07	Intronic	0
TXNRD1	TRXR1-04	rs10861201	0.23	Intronic	0
TXNRD2	TRXR2-01	rs2073752	0.28	Missense	370	T>I
TXNRD2	TRXR2-03	rs5748469	0.33	Missense	66	S>A
TXNRD2	TRXR2-04	rs756661	0.47	Intronic	0
TXNRD2	TRXR2-05	rs2020917	0.28	Intronic	0
TXNRD2	TRXR2-07	rs740603	0.46	Intergenic	0
TXNRD2	TRXR2-08	rs4485648	0.20	Intronic	0
TXNRD2	TRXR2-09	rs732262	0.09	Intronic	0
TXNRD2	TRXR2-10	rs1548357	0.27	Intronic	0
TXNRD2	TRXR2-11	rs2073750	0.21	Intronic	0
TXNRD2	TRXR2-12	rs3788306	0.30	Intronic	0

^adb: rs number for each SNP which uniquely identifies it.

^bMAF: minor allele frequency.

^cLabels for amino acids: aspartic acid (D); proline (P); valine (V); alanine (A); threonine (T); isoleucine (I); serine (S).

^dUTR: untranslated region.