Table 5. Genotype frequencies and effect sizes for most significant two-way interaction with logistic regression.
TRXR2-04
|
||||
---|---|---|---|---|
0 | 1 | 2 | Total | |
TRX1-14 | ||||
0 | 362/441 | 700/622 | 291/292 | 1353/1355 |
1 (N/A) | 0.73 (0.61–0.87) | 0.82 (0.67–1.02) | 1 (N/A) | |
1 | 226/196 | 388/365 | 178/121 | 792/682 |
0.71 (0.56–0.90) | 0.77 (0.63–0.94) | 0.56 (0.43–0.73) | 0.86 (0.76–0.98) | |
2 | 37/37 | 57/66 | 19/34 | 113/137 |
0.82 (0.51–1.32) | 0.95 (0.65–1.39) | 1.47 (0.82–2.62) | 1.21 (0.92–1.58) | |
Total | ||||
625/674 | 1145/1053 | 488/447 | ||
1 (N/A) | 0.85 (0.74–0.98) | 0.85 (0.72–1.01) |
Genotype frequencies and effect sizes for most significant two-way interaction with logistic regression. Loci: TRX1-14 and TRXR2-04. At each locus: 0=common homozygote, 1=heterozygote and 2=rare homozygote. In each cell: controls/cases; odds ratio (95% confidence interval). The log-likelihood ratio statistic is 14.77 (P=0.00026, 8 df).