Table 5. Genotype frequencies and effect sizes for most significant two-way interaction with logistic regression.

	TRXR2-04
	0	1	2	Total
TRX1-14
0	362/441	700/622	291/292	1353/1355
	1 (N/A)	0.73 (0.61–0.87)	0.82 (0.67–1.02)	1 (N/A)
1	226/196	388/365	178/121	792/682
	0.71 (0.56–0.90)	0.77 (0.63–0.94)	0.56 (0.43–0.73)	0.86 (0.76–0.98)
2	37/37	57/66	19/34	113/137
	0.82 (0.51–1.32)	0.95 (0.65–1.39)	1.47 (0.82–2.62)	1.21 (0.92–1.58)
Total
	625/674	1145/1053	488/447
	1 (N/A)	0.85 (0.74–0.98)	0.85 (0.72–1.01)

Genotype frequencies and effect sizes for most significant two-way interaction with logistic regression. Loci: TRX1-14 and TRXR2-04. At each locus: 0=common homozygote, 1=heterozygote and 2=rare homozygote. In each cell: controls/cases; odds ratio (95% confidence interval). The log-likelihood ratio statistic is 14.77 (P=0.00026, 8 df).