Figure 2.

Antitumour activity. Changes in the LLC tumour growth rates in the mice. (A) Mice receiving TXL-alone (•), NK105-alone (○), combined treatment with PTX and radiation (▪), and combined treatment with NK105 and radiation (□) were administered a single i.v. injection of PTX or NK105 at the dose 45 mg kg⁻¹ on day 14 after the tumour inoculation (=on day 0 after the initial treatment). After 24 h the drugs were administered, the mice in the radiation-alone (▵) and the combined-treatment groups were irradiated (arrow). Mice in the control group (×) were given no treatment. (B) Changes in the relative body weight. Data were derived from the same mice as those used in the present study.