Table 1. Percentage of methylation (NIM) and tumour stage/grade in TCC.

	APAF-1			DAPK-1
	G1/2	G3	P-value	G1/2	G3	P-value
pTa
Median	20	53.4		34.1	3.6
Mean	22.7	49.6		37.2	17.6
STD	14.7	17.8		37.1	23.5
n	14	6		14	6
P-value	0.002*			0.6*
			0.001**			0.8**
pT1
Median	53.5	71		18.3	24
Mean	62.8	66.4		27.4	41.3
STD	29.7	19.4		29.1	47.9
n	10	20		10	20
P-value	0.4*			0.7*
			0.001***			0.09***
⩾pT2
Median	n.o.	97.5		n.o.	1
Mean		94.1			15.8
STD		27.1			35.4
n		30			30

NIM=normalised index of methylation; n.o.=not observed; STD=standard deviation; TCC=transitional cell carcinoma.

^*G1/2 vs G3 tumours.

^**pTa vs pT1 tumours.

^***pT1 vs ⩾pT2 tumours.

Normal bladder tissue (n=20): APAF-1 median (0%), mean (7%), STD (17.3%)/DAPK-1 median (0%), mean (5%), STD (15.5%).