Table 3. Association of magnetic field exposure and outcome: Cox proportional hazards regression analyses.
Event-free survival
|
Survival
|
|||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Variable | No. of cases | No. faileda | HR | 95% HR CIb | P c | No. of cases | No. failed | HR | 95% HR CI | Pc | ||
Univariate analysis | 386 | 73 | 0.4 | 386 | 30 | 0.2 | ||||||
<0.1 μT | 251 | 42 | 1.00 | 251 | 17 | 1.00 | ||||||
0.1–0.19 μT | 95 | 22 | 1.47 | 0.88 | 2.46 | 95 | 8 | 1.27 | 0.55 | 2.93 | ||
0.2–0.29 μT | 21 | 4 | 1.15 | 0.41 | 3.20 | 21 | 1 | 0.68 | 0.09 | 5.13 | ||
⩾0.3 μT | 19 | 5 | 1.66 | 0.66 | 4.18 | 19 | 4 | 3.39 | 1.14 | 10.06 | ||
Multivariate analysis | ||||||||||||
B-precursord | 361 | 70 | 0.5 | 361 | 28 | 0.06 | ||||||
NCI risk group | 1.76 | 1.01 | 2.88 | 2.78 | 1.29 | 5.96 | ||||||
SES | 0.98 | 0.52 | 1.83 | 1.61 | 0.68 | 3.82 | ||||||
<0.1 μT | 235 | 41 | 1.00 | 235 | 16 | 1.00 | ||||||
0.1–0.19 μT | 89 | 20 | 1.25 | 0.72 | 2.19 | 89 | 7 | 1.16 | 0.47 | 2.84 | ||
0.2–0.29 μT | 19 | 4 | 1.32 | 0.47 | 3.71 | 19 | 1 | 0.85 | 0.11 | 6.40 | ||
⩾0.3 μT | 18 | 5 | 1.92 | 0.75 | 4.90 | 18 | 4 | 4.53 | 1.49 | 13.76 |
Failure events defined as failure to attain complete response during induction therapy, leukaemia relapse, secondary cancer, or death.
HR=hazard ratio; CI=confidence interval.
Test of trend for time-weighted average magnetic field exposure level.
Adjusted for National Cancer Institute (NCI) risk group and socioeconomic status (SES).