Table 3. Predictive value of tumour budding, lymphatic invasion and combination of budding and lymphatic invasion for lymph nodes metastasis.
|
Lymph node metastasis (including ITCs and micrometastasis)
|
Sensitivity (%) | Specificity (%) | Positive predictive value (%) | Negative predictive value (%) | ||
|---|---|---|---|---|---|---|
| Present | Absent | |||||
| Lymphatic invasion | ||||||
| Present | 6 | 1 | 37.5 | 97.5 | 85.7 | 79.6 |
| Absent | 10 | 39 | ||||
| Tumour budding | ||||||
| Present | 16 | 26 | 100.0 | 65.0 | 38.1 | 100.0 |
| Absent | 0 | 14 | ||||
| Lymphatic invasion or tumour budding | ||||||
| Present | 16 | 26 | 100.0 | 65.0 | 38.1 | 100.0 |
| Absent | 0 | 14 | ||||
| Lymphatic invasion and tumour budding | ||||||
| Present | 7 | 0 | 43.7 | 100.0 | 100.0 | 81.6 |
| Absent | 9 | 40 | ||||
ITC=isolated tumour cells.