Table 1. Correlation between MTHFR, MTR and TS genotypes and clinically determined tumour regression following polychemotherapy in multimodally treated oesophageal SCCa.
| Genotypes | Complete remission/partial remission (%) | No change/progression (%) |
|---|---|---|
| MTHFR 677CC | 12 (46.2) | 14 (53.8) |
| MTHFR 677CT/677TT | 19 (46.3) | 22 (53.7) |
| MTR 2756AA | 20 (45.5) | 24 (54.5) |
| MTR 2756AG/2756GG | 9 (45.0) | 11 (55.0) |
| TS 2R/2R | 15 (45.5) | 18 (54.5) |
| TS 2R/3R/3R/3R | 12 (50.0) | 12 (50.0) |
a
No significant correlations according to χ2 test.