Table 3. Methods of detection and treatment of breast cancer according to family history.
|
Familial risk
|
||||
|---|---|---|---|---|
| High familial risk (n=58) | Low familial risk (n=575) | Unadjusted OR (95% CI) | Multi-adjusted OR (95% CI) | |
| Method of detection | ||||
| Self examination | 22 (38%) | 213 (37%) | 1a | 1a,b |
| Surveillance | 16 (28%) | 132 (23%) | 1.2 (0.6–2.3) | 1.3 (0.7–2.8) |
| Symptoms | 17 (29%) | 203 (35%) | 0.8 (0.4–1.6) | 0.7 (0.4–1.4) |
| Fortuitous | 3 (5%) | 17 (3%) | 1.7 (0.5–6.3) | 1.8 (0.5–7.0) |
| Unknown | 0 (0%) | 10 (2%) | — | — |
| Locoregional treatment | ||||
| Breast-conserving surgery | 36 (62%) | 338 (59%) | 1a, | 1a,b |
| Mastectomy | 14 (24%) | 164 (29%) | 0.8 (0.4–1.5) | 0.7 (0.3–1.2) |
| Bilateral mastectomy | 3 (5%) | 6 (1%) | 4.7 (1.1–19.6)* | 4.2 (0.9–18.4) |
| Other | 5 (9%) | 67 (12%) | 0.7 (0.3–1.9) | 0.6 (0.2–1.7) |
| Chemotherapy | ||||
| No | 15 (26%) | 201 (35%) | 1a | 1a,c |
| Yes | 43 (74%) | 374 (65%) | 1.5 (0.8–2.8) | 1.3 (0.6–2.7) |
| Hormonotherapy | ||||
| No | 25 (43%) | 345 (60%) | 1a | 1a,d |
| Yes | 33 (57%) | 230 (40%) | 2.0 (1.1–3.4)* | 1.9 (1.1–3.4)* |
OR=odds ratio;
a
Reference category.
b
Adjusted for age and stage at diagnosis.
c
Adjusted for age, stage at diagnosis, locoregional treatment, oestrogen receptor status and use of hormotherapy.
d
Adjusted for age, stage at diagnosis, locoregional treatment, oestrogen receptor status and use of chemotherapy.
*
P<0.05.