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. 2008 May 16;4(5):e1000066. doi: 10.1371/journal.ppat.1000066

Figure 1. Circulating apoptosis markers in patients with valvulopathy.

Figure 1

A, The circulating levels of nucleosomes was determined by immunoassays in control subjects, patients with acute Q fever, valvulopathy, acute Q fever with valvulopathy and Q fever endocarditis. Results are expressed as individual values with medians. B–E, Active caspases were detected through FLICA fluorescence (FL1 channel) and flow cytometry analysis of leukocytes from patients with acute Q fever (B), valvulopathy (C), acute Q fever with valvulopathy (D) and Q fever endocarditis (E) compared to control subjects (gray line). F, The results are expressed as percentage of active caspases for each individual. Bars represent the median of the values. G, Active caspases were quantified in CD3+ and CD14+ leukocytes from control subjects and patients. The results represent the mean±SEM. * p<0.01 and ** p<0.001.