Table 1. Patient characteristics.

	Patients
Characteristic	No.	%
Total	47	100
Male	35	74
Female	12	26
Age (years)
Median	62
Range	18–93
Disease at time of commencing IRESSA
Locally recurrent	29	62
Metastatica	18	38
Histology
Squamous cell carcinoma	45	96
UCNTb	1	2
Carcinosarcoma	1	2
ECOG performance status
0	0	0
1	26	55
2	19	40
3	2	4
Prior therapy (n=43)
Surgery	22	51
Radiotherapy	40	93
With chemotherapy	18	42
Alone (radical or palliative)	22	51
Chemotherapy	27	63
Radical chemoradiation only	11	26
Radical chemoradiation and then for recurrence or metastases	7	16
Only for recurrent disease or metastases	9	21

^aThese patients may also have had local recurrence simultaneously with metastatic disease.

^bUndifferentiated carcinoma of nasopharyngeal type.