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. 2006 Feb 21;94(5):743–751. doi: 10.1038/sj.bjc.6602982

Table 3. Host factors and risk of skin tumours.

  Controls CMM
SCC
BCC
  N N Crude OR Adj ORa N Crude OR Adj ORa N Crude OR Adj ORa
Hair colour
Dark 156 46 1 1 39 1 1 63 1 1
Brown 127 103 2.7 2.6 58 1.8 2.1 82 1.6 1.7
      (1.81–4.18) (1.63–4.20)   (1.14–2.92) (1.21–3.50)   (1.07–2.39) (1.08–2.59)
Blonde 41 41 3.4 2.7 26 2.5 2.6 42 2.5 2.2
      (1.97–5.84) (1.43–5.03)   (1.39–4.64) (1.29–5.07)   (1.51–4.27) (1.27–3.91)
Light blonde/Red 25 24 3.3 1.9 16 2.6 1.9 28 2.8 2.3
      (1.70–6.23) (0.87–4.00)   (1.27–5.25) (0.85–4.40)   (1.50–5.12) (1.15–4.49)
P-linear trend     P<0.001 P<0.001   P=0.002 P=0.003   P<0.001 P<0.001
                     
Eye colour
Dark 110 44 1 1 28 1 1 37 1 1
Chesnut 96 57 1.5 1.2 33 1.3 1.2 48 1.5 1.3
      (0.92–2.40) (0.70–2.17)   (0.76–2.40) (0.62–2.16)   (0.89–2.47) (0.75–2.18)
Green 42 50 3.0 3.2 26 2.4 1.9 56 4.0 3.4
      (1.74–5.10) (1.69–6.04)   (1.28–4.62) (0.90–3.95)   (2.29–6.85) (1.92–6.22)
Blue/Grey 68 37 1.4 1.3 30 1.7 1.2 45 2.0 1.4
      (0.80–2.31) (0.67–2.49)   (0.95–3.15) (0.57–2.33)   (1.16–3.34) (0.77–2.56)
Light blue 33 26 2.0 1.7 22 2.6 1.6 29 2.6 1.8
      (1.06–3.67) (0.80–3.68)   (1.32–5.17) (0.76–3.95)   (1.40–4.87) (0.94–3.66)
P-linear trend     P=0.005 P<0.001   P=0.010 P=0.011   P<0.001 P<0.001
                     
Tendency to tan
Tan 178 89 1 1 40 1 1 90 1 1
No Tan 171 125 1.5 1.2 99 2.6 2.7 125 1.4 1.5
      (1.04–2.06) (0.77–1.77)   (1.69–3.93) (1.67–4.27)   (1.03–2.04) (1.01–2.12)
                     
Tendency to sunburn
No sunburns 52 25 1 1 23 1 1 24 1 1
Sunburn/Blisters 297 189 1.3 0.8 116 0.9 0.6 191 1.4 1.0
      (0.79–2.21) (0.46–1.48)   (0.52–1.51) (0.31–1.06)   (0.83–2.34) (0.59–1.78)
                     
Number of naevi (forearm count)
0 177 60 1 1 81 1 1 105 1 1
1–5 102 69 2.0 1.4 34 0.7 0.7 76 1.3 1.2
      (1.31–3.05) (0.85–2.26)   (0.46–1.16) (0.42–1.25)   (0.86–1.84) (0.78–1.85)
                     
6–10 32 38 3.5 1.9 14 1.0 1.1 16 0.8 0.8
      (2.01–6.10) (0.98–3.63)   (0.48–1.89) (0.49–2.50)   (0.44–1.61) (0.37–1.61)
                     
11+ 38 47 3.6 1.5 10 0.6 0.4 18 0.8 0.7
      (2.17–6.13) (0.72–2.82)   (0.27–1.21) (0.16–1.13)   (0.43–1.47) (0.35–1.47)
P-linear trend     P<0.001 P<0.001   P=0.176 P=0.530   P=0.697 P=0.754
                     
Number of moles>10 mm
No 327 193 1 1 126 1 1 195 1 1
Yes 22 21 1.6 0.9 13 1.5 2.0 20 1.5 1.6
      (0.87–3.02) (0.41–1.99)   (0.75–3.14) (0.83–4.68)   (0.81–2.86) (0.79–3.32)
                     
Number of naevi (Chart)
No moles 140 30 1 1 70 1 1 78 1 1
Some 186 121 3.0 2.4 59 0.6 0.8 120 1.2 1.2
      (1.92–4.79) (1.42–4.14)   (0.42–0.96) (0.48–1.33)   (0.81–1.66) (0.82–1.91)
Several 23 63 12.8 8.4 10 0.9 1.7 17 1.3 1.5
      (6.88–23.74) (3.92–18.13)   (0.39–1.93) (0.62–4.64)   (0.67–2.63) (0.68–3.38)
P-linear trend     P<0.001 P<0.001   P=0.170 P=0.806   P=0.346 P=0.139
                     
Freckles
None 289 131 1 1 107 1 1 155 1 1
Some/Several 60 83 3.1 2.3 32 1.4 1.6 60 1.9 1.6
      (2.06–4.51) (1.43–3.60)   (0.89–2.34) (0.93–2.87)   (1.24–2.80) (1.00–2.51)
a

Adjusted by age and country of interview and all other variables in the table.