Table 3. Host factors and risk of skin tumours.
Controls |
CMM
|
SCC
|
BCC
|
|||||||
---|---|---|---|---|---|---|---|---|---|---|
N | N | Crude OR | Adj ORa | N | Crude OR | Adj ORa | N | Crude OR | Adj ORa | |
Hair colour | ||||||||||
Dark | 156 | 46 | 1 | 1 | 39 | 1 | 1 | 63 | 1 | 1 |
Brown | 127 | 103 | 2.7 | 2.6 | 58 | 1.8 | 2.1 | 82 | 1.6 | 1.7 |
(1.81–4.18) | (1.63–4.20) | (1.14–2.92) | (1.21–3.50) | (1.07–2.39) | (1.08–2.59) | |||||
Blonde | 41 | 41 | 3.4 | 2.7 | 26 | 2.5 | 2.6 | 42 | 2.5 | 2.2 |
(1.97–5.84) | (1.43–5.03) | (1.39–4.64) | (1.29–5.07) | (1.51–4.27) | (1.27–3.91) | |||||
Light blonde/Red | 25 | 24 | 3.3 | 1.9 | 16 | 2.6 | 1.9 | 28 | 2.8 | 2.3 |
(1.70–6.23) | (0.87–4.00) | (1.27–5.25) | (0.85–4.40) | (1.50–5.12) | (1.15–4.49) | |||||
P-linear trend | P<0.001 | P<0.001 | P=0.002 | P=0.003 | P<0.001 | P<0.001 | ||||
Eye colour | ||||||||||
Dark | 110 | 44 | 1 | 1 | 28 | 1 | 1 | 37 | 1 | 1 |
Chesnut | 96 | 57 | 1.5 | 1.2 | 33 | 1.3 | 1.2 | 48 | 1.5 | 1.3 |
(0.92–2.40) | (0.70–2.17) | (0.76–2.40) | (0.62–2.16) | (0.89–2.47) | (0.75–2.18) | |||||
Green | 42 | 50 | 3.0 | 3.2 | 26 | 2.4 | 1.9 | 56 | 4.0 | 3.4 |
(1.74–5.10) | (1.69–6.04) | (1.28–4.62) | (0.90–3.95) | (2.29–6.85) | (1.92–6.22) | |||||
Blue/Grey | 68 | 37 | 1.4 | 1.3 | 30 | 1.7 | 1.2 | 45 | 2.0 | 1.4 |
(0.80–2.31) | (0.67–2.49) | (0.95–3.15) | (0.57–2.33) | (1.16–3.34) | (0.77–2.56) | |||||
Light blue | 33 | 26 | 2.0 | 1.7 | 22 | 2.6 | 1.6 | 29 | 2.6 | 1.8 |
(1.06–3.67) | (0.80–3.68) | (1.32–5.17) | (0.76–3.95) | (1.40–4.87) | (0.94–3.66) | |||||
P-linear trend | P=0.005 | P<0.001 | P=0.010 | P=0.011 | P<0.001 | P<0.001 | ||||
Tendency to tan | ||||||||||
Tan | 178 | 89 | 1 | 1 | 40 | 1 | 1 | 90 | 1 | 1 |
No Tan | 171 | 125 | 1.5 | 1.2 | 99 | 2.6 | 2.7 | 125 | 1.4 | 1.5 |
(1.04–2.06) | (0.77–1.77) | (1.69–3.93) | (1.67–4.27) | (1.03–2.04) | (1.01–2.12) | |||||
Tendency to sunburn | ||||||||||
No sunburns | 52 | 25 | 1 | 1 | 23 | 1 | 1 | 24 | 1 | 1 |
Sunburn/Blisters | 297 | 189 | 1.3 | 0.8 | 116 | 0.9 | 0.6 | 191 | 1.4 | 1.0 |
(0.79–2.21) | (0.46–1.48) | (0.52–1.51) | (0.31–1.06) | (0.83–2.34) | (0.59–1.78) | |||||
Number of naevi (forearm count) | ||||||||||
0 | 177 | 60 | 1 | 1 | 81 | 1 | 1 | 105 | 1 | 1 |
1–5 | 102 | 69 | 2.0 | 1.4 | 34 | 0.7 | 0.7 | 76 | 1.3 | 1.2 |
(1.31–3.05) | (0.85–2.26) | (0.46–1.16) | (0.42–1.25) | (0.86–1.84) | (0.78–1.85) | |||||
6–10 | 32 | 38 | 3.5 | 1.9 | 14 | 1.0 | 1.1 | 16 | 0.8 | 0.8 |
(2.01–6.10) | (0.98–3.63) | (0.48–1.89) | (0.49–2.50) | (0.44–1.61) | (0.37–1.61) | |||||
11+ | 38 | 47 | 3.6 | 1.5 | 10 | 0.6 | 0.4 | 18 | 0.8 | 0.7 |
(2.17–6.13) | (0.72–2.82) | (0.27–1.21) | (0.16–1.13) | (0.43–1.47) | (0.35–1.47) | |||||
P-linear trend | P<0.001 | P<0.001 | P=0.176 | P=0.530 | P=0.697 | P=0.754 | ||||
Number of moles>10 mm | ||||||||||
No | 327 | 193 | 1 | 1 | 126 | 1 | 1 | 195 | 1 | 1 |
Yes | 22 | 21 | 1.6 | 0.9 | 13 | 1.5 | 2.0 | 20 | 1.5 | 1.6 |
(0.87–3.02) | (0.41–1.99) | (0.75–3.14) | (0.83–4.68) | (0.81–2.86) | (0.79–3.32) | |||||
Number of naevi (Chart) | ||||||||||
No moles | 140 | 30 | 1 | 1 | 70 | 1 | 1 | 78 | 1 | 1 |
Some | 186 | 121 | 3.0 | 2.4 | 59 | 0.6 | 0.8 | 120 | 1.2 | 1.2 |
(1.92–4.79) | (1.42–4.14) | (0.42–0.96) | (0.48–1.33) | (0.81–1.66) | (0.82–1.91) | |||||
Several | 23 | 63 | 12.8 | 8.4 | 10 | 0.9 | 1.7 | 17 | 1.3 | 1.5 |
(6.88–23.74) | (3.92–18.13) | (0.39–1.93) | (0.62–4.64) | (0.67–2.63) | (0.68–3.38) | |||||
P-linear trend | P<0.001 | P<0.001 | P=0.170 | P=0.806 | P=0.346 | P=0.139 | ||||
Freckles | ||||||||||
None | 289 | 131 | 1 | 1 | 107 | 1 | 1 | 155 | 1 | 1 |
Some/Several | 60 | 83 | 3.1 | 2.3 | 32 | 1.4 | 1.6 | 60 | 1.9 | 1.6 |
(2.06–4.51) | (1.43–3.60) | (0.89–2.34) | (0.93–2.87) | (1.24–2.80) | (1.00–2.51) |
Adjusted by age and country of interview and all other variables in the table.