Table 2. Treatment details by chemotherapy cycle.

	Cycle number
	1	2	3	4
Number of cycles	37	36	36	32
Dose modification	1	2	7	12
Reasons
Haematological toxicity		1	2	5
Other toxicity		1	5	7
Dose delay	1	3	13	14
Reasons
Hyponatraemia	1
Haematological toxicity		3	11	9
Other toxicity			2	5
Hospitalisation	9	11	15	7