Figure 5.
Stathmin mRNA expression status in primary OSCCs and OSCC-derived cell lines. (A) Comparison of stathmin mRNA expression levels between stathmin-positive and stathmin-negative cases classified by immunohistochemistry analysis. There is a significant difference in the stathmin mRNA expression levels between negative and positive cases (P<0.001, Mann–Whitney U-test). (B) Quantification of mRNA levels in OSCC-derived cell lines by qRT–PCR analysis. Significant upregulation of the stathmin gene is seen in all OSCC-derived cell lines compared to stathmin mRNA expression in HNOKs. Data are expressed as means±s.d.