Table 4. Grades 3 and 4 toxicities in trial B.

	Gastrazole (n=53) (%)	5-FU (n=42) (%)	P-values for trend
Diarrhoea	2	7	0.03
Stomatitis	0	5	<0.001
Hand foot syndrome	0	2	<0.001
Nausea	8	5	0.76
Vomiting	9	7	0.64
Lethargy	36	33	0.95
Infection	15	10	0.34
Anaemia	6	16	0.72
Thrombocytopenia	2	3	0.82
Neutropenia	2	3	0.14

5-FU=5-fluorouracil.