Table 5. Quality of life scores in trial B.

	Baseline			6 weeks			12 weeks
	Mean	s.d.	P-value	Mean	Diff from base	P-value	Mean	Diff from base	P-value
Functioning scales
Physical
Gastrazole	73.6	21.1	0.97	66.0	−6.16	0.34	66.6	−6.75	0.39
5-FU	73.3	21.3		74.1	−3.92		75.4	−0.47
Role
Gastrazole	53.6	35.7	0.30	51.9	−3.48	0.38	58.8	2.00	0.43
5-FU	63.1	27.8		32.2	−12.12		61.4	−10.00
Emotional
Gastrazole	71.1	22.4	0.76	70.6	−0.12	0.64	65.5	−0.80	0.93
5-FU	71.9	23.4		77.8	3.25		75.5	2.20
Cognitive
Gastrazole	78.4	19.5	0.87	73.9	0	0.96	75.1	−5.53	0.18
5-FU	78.9	19.2		79.4	−0.52		83.3	4.25
Social
Gastrazole	62.4	33.5	0.55	54.3	−1.88	0.08	54.2	−16.50	0.33
5-FU	69.0	25.5		56.3	−15.52		29.7	−5.25
Global
Gastrazole	61.4	21.9	0.42	54.5	−7.35	0.35	56.2	−8.36	0.22
5-FU	57.05	21.0		61.2	−0.33		67.7	2.00
Symptom scales
Fatigue
Gastrazole	43.3	27.3	0.98	48.6	5.92	0.95	55.0	17.64	0.16
5-FU	42.8	23.1		43.6	6.54		38.5	4.14
N&V
Gastrazole	17.1	23.6	0.94	21.5	5.00	0.36	22.0	6.50	0.37
5-FU	19.3	25.8		15.6	−2.36		15.6	−2.27
Pain
Gastrazole	34.9	28.5	0.82	42.2	2.67	0.61	45.7	4.86	0.16
5-FU	35.6	28.5		33.9	1.27		22.9	−4.79
Dyspnoea
Gastrazole	21.2	25.0	<0.01	25.8	6.68	0.51	29.6	12.56	0.07
5-FU	7.0	15.8		9.5	4.93		4.1	−2.20
Sleep disturbance
Gastrazole	34.8	28.8	0.46	31.0	1.22	0.15	22.7	−5.56	0.33
5-FU	31.6	34.7		25.4	−10.45		10.3	22.27
Appetite
Gastrazole	39.9	40.6	0.67	50.6	11.26	0.99	50.8	12.94	0.09
5-FU	36.7	39.6		42.2	9.24		27.0	−4.53
Constipation
Gastrazole	24.2	34.0	0.24	19.8	1.27	0.28	14.6	−9.0	0.36
5-FU	31.6	32.9		17.8	−15.0		13.7	0
Diarrhoea
Gastrazole	15.1	25.4	0.75	17.3	1.27	0.81	26.7	11.13	0.48
5-FU	17.5	27.7		20.72	2.43		21.5	−0.06
Financial
Gastrazole	34.1	38.2	0.36	28.4	−7.96	0.88	24.4	−7.62	0.68
5-FU	27.9	38.1		25.6	−3.54		23.5	−10.38

N&V=nausea and vomiting; s.d.=standard deviation; Diff from base=difference from baseline.