Table 3. Novel genes identified by DDD.

Symbol	Name	UniGene ID	GAa	Non cancera	Cancera	Function
AGR2	Arginase, type II	Hs.226391	0.00242	0.00012	0.00017	Urea cycle
ANKRD9	Ankyrin repeat domain 9	Hs.432945	0.00098	0.00002	0.00004	Function unknown
ARHGEF16	Rho guanine exchange factor 16	Hs.87435	0.00032	0.00002	0.00002	Function unknown
BENE	BENE protein	Hs.185055	0.00059	0.00003	0.00004	Function unknown
C8G	Complement component 8, gamma polypeptide	Hs.1285	0.00016	0.00000	0.00000	Complement activation
CLDN18	Claudin 18	Hs.278966	0.00043	0.00003	0.00001	Tight junction component
CLDN2	Claudin 2	Hs.16098	0.00023	0.00002	0.00002	Tight junction component
EPS8L3	EPS8-like 3	Hs.5366	0.00021	0.00001	0.00002	Receptor activity
FBXL6	F-box and leucine-rich repeat protein 6	Hs.12271	0.00037	0.00002	0.00003	Ubiquitin cycle
GEFT	RAC/CDC42 exchange factor	Hs.61581	0.00027	0.00002	0.00003	Cell proliferation
KIAA1706	KIAA1706 protein	Hs.412318	0.00034	0.00003	0.00001	DNA binding
KREMEN2	Kringle containing transmembrane protein 2	Hs.73452	0.00043	0.00000	0.00004	Wnt signaling pathway
MEIS4	Likely ortholog of mouse myeloid ecotropic viral integration site-related gene 2	Hs.356135	0.00043	0.00002	0.00004	Transcription regulation
MYEOV	Myeloma overexpressed gene	Hs.436000	0.00048	0.00000	0.00004	Nucleic acid binding
NET1	Neuroepithelial cell transforming gene 1	Hs.25155	0.00100	0.00008	0.00008	Regulation of cell growth
NOS3	Nitric-oxide synthase activity	Hs.511603	0.00027	0.00002	0.00001	Nitric-oxide synthase activity
PARD6G	Par-6 partitioning defective 6 homolog gamma (Caenorhabditis elegans)	Hs.223584	0.00037	0.00001	0.00001	Cytokinesis
PTK2B	Protein tyrosine kinase 2 beta	Hs.438975	0.00094	0.00004	0.00005	Signal transduction
S100A14	S100 calcium binding protein A14	Hs.288998	0.00041	0.00001	0.00003	Calcium ion binding
SMCX	Smcx homolog, X chromosome (mouse)	Hs.103381	0.00066	0.00004	0.00004	Transcription regulation
THBS3	Thrombospondin 3	Hs.169875	0.00046	0.00004	0.00003	Cell-matrix adhesion
UNC93A	Unc-93 homolog A (C. elegans)	Hs.267749	0.00027	0.00000	0.00000	Function unknown
WBSCR21	Williams beuren syndrome chromosome region 21	Hs.182476	0.00043	0.00002	0.00004	Aromatic compound metabolism

^aFraction of sequences mapping to UniGene cluster.